Biology:Nucleoside ribosyltransferase

From HandWiki
Short description: Class of enzymes
nucleoside ribosyltransferase
Identifiers
EC number2.4.2.5
CAS number9030-31-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a nucleoside ribosyltransferase (EC 2.4.2.5) is an enzyme that catalyzes the chemical reaction

D-ribosyl-base1 + base2 [math]\displaystyle{ \rightleftharpoons }[/math] D-ribosyl-base2 + base1

Thus, the two substrates of this enzyme are D-ribosyl-base1 and base2, whereas its two products are D-ribosyl-base2 and base1.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is nucleoside:purine(pyrimidine) D-ribosyltransferase. This enzyme is also called nucleoside N-ribosyltransferase.

References

  • "Some enzymes of nucleoside metabolism of Escherichia coli". The Journal of Biological Chemistry 223 (1): 535–49. November 1956. PMID 13376622.