Biology:Renal tissue kallikrein
From HandWiki
| Tissue kallikrein | |||||||||
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| Identifiers | |||||||||
| EC number | 3.4.21.35 | ||||||||
| CAS number | 389069-73-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Tissue kallikrein (EC 3.4.21.35, glandular kallikrein, pancreatic kallikrein, submandibular kallikrein, submaxillary kallikrein, kidney kallikrein, urinary kallikrein, kallikrein, salivary kallikrein, kininogenin, kininogenase, callicrein, glumorin, padreatin, padutin, kallidinogenase, bradykininogenase, depot-padutin, urokallikrein, dilminal D, onokrein P) is an enzyme.[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] This enzyme catalyses the following chemical reaction
- Preferential cleavage of Arg- bonds in small molecule substrates. It acts highly selectively to release kallidin (lysyl-bradykinin) from kininogen
This enzyme is formed from tissue prokallikrein by activation with trypsin.
See also
References
- ↑ Porcine glandular kallikreins. Methods in Enzymology. 80 Pt C. 1981. pp. 493–532. doi:10.1016/s0076-6879(81)80042-0.
- ↑ "Partial amino-acid sequence of the epidermal growth-factor-binding protein". European Journal of Biochemistry 129 (2): 365–71. December 1982. doi:10.1111/j.1432-1033.1982.tb07059.x. PMID 6295764.
- ↑ "Effect of substrate size on tonin activity". Biochemical and Biophysical Research Communications 108 (4): 1441–6. October 1982. doi:10.1016/s0006-291x(82)80068-5. PMID 6295383.
- ↑ "Kinetic studies of rat renin and tonin on purified rat angiotensinogen". Canadian Journal of Biochemistry and Cell Biology 62 (2–3): 137–42. 1984. doi:10.1139/o84-020. PMID 6097352.
- ↑ "Demonstration of arginyl-bradykinin moiety in rat HMW kininogen: direct evidence for liberation of bradykinin by rat glandular kallikreins". Biochemical and Biophysical Research Communications 127 (1): 289–95. February 1985. doi:10.1016/s0006-291x(85)80157-1. PMID 3844939.
- ↑ "The chymotrypsin-like activity of human prostate-specific antigen, gamma-seminoprotein". FEBS Letters 225 (1–2): 168–72. December 1987. doi:10.1016/0014-5793(87)81151-1. PMID 3691800.
- ↑ "Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus". The Journal of Biological Chemistry 262 (17): 8027–34. June 1987. PMID 3036794.
- ↑ "Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin". European Journal of Biochemistry 163 (2): 303–12. March 1987. doi:10.1111/j.1432-1033.1987.tb10801.x. PMID 3643848.
- ↑ "Rat submaxillary gland serine protease, tonin. Structure solution and refinement at 1.8 A resolution". Journal of Molecular Biology 195 (2): 373–96. May 1987. doi:10.1016/0022-2836(87)90658-9. PMID 2821276.
- ↑ "Characterization of serine proteinases isolated from rat submaxillary gland: with special reference to the degradation of rat kininogens by these enzymes". Journal of Biochemistry 102 (6): 1389–404. December 1987. doi:10.1093/oxfordjournals.jbchem.a122185. PMID 3482210.
- ↑ Rat pancreas kallikrein. Methods in Enzymology. 163. 1989. pp. 115–28. doi:10.1016/0076-6879(88)63013-8.
- ↑ "Substrate specificities of growth factor associated kallikreins of the mouse submandibular gland". Biochemistry 28 (19): 7813–9. September 1989. doi:10.1021/bi00445a043. PMID 2611215.
- ↑ Rat urinary kallikrein. Methods in Enzymology. 163. 1988. pp. 128–43. doi:10.1016/0076-6879(88)63014-x.
- ↑ Human tissue kallikrein. Methods in Enzymology. 163. 1988. pp. 102–15. doi:10.1016/0076-6879(88)63012-6.
- ↑ "Selective cleavage at lysine of the 50 kDa-20 kDa connector loop segment of skeletal myosin S-1 by endoproteinase Arg-C". FEBS Letters 246 (1–2): 171–6. March 1989. doi:10.1016/0014-5793(89)80277-7. PMID 2523317.
- ↑ "Organization and expression of the rat kallikrein gene family". The Journal of Biological Chemistry 264 (13): 7653–62. May 1989. PMID 2708383.
- ↑ "Substrate specificity of two kallikrein family gene products isolated from the rat submaxillary gland". FEBS Letters 265 (1–2): 137–40. June 1990. doi:10.1016/0014-5793(90)80903-v. PMID 2194829.
- ↑ "Purification and characterization of a kallikrein-like T-kininogenase". The Journal of Biological Chemistry 265 (5): 2822–7. February 1990. PMID 2303430.
External links
- Tissue+kallikrein at the US National Library of Medicine Medical Subject Headings (MeSH)
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