Biology:Scutelarin

From HandWiki
Scutelarin
Identifiers
EC number3.4.21.60
CAS number93389-45-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Scutelarin (EC 3.4.21.60, taipan activator, Oxyuranus scutellatus prothrombin-activating proteinase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Selective cleavage of Arg-Thr and Arg-Ile in prothrombin to form thrombin and two inactive fragments

This enzyme is isolated from the venom of the Taipan snake (Oxyuranus scutellatus).

References

  1. "Characterization of the prothrombin activator from the venom of Oxyuranus scutellatus scutellatus (taipan venom)". Biochemistry 19 (5): 1020–3. March 1980. doi:10.1021/bi00546a029. PMID 6986908. 
  2. "Prothrombin activation by an activator from the venom of Oxyuranus scutellatus (Taipan snake)". The Journal of Biological Chemistry 261 (28): 13258–67. October 1986. PMID 3531198. 

External links