Biology:Snake venom factor V activator

From HandWiki
Snake venom factor V activator
Identifiers
EC number3.4.21.95
CAS number471269-12-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Snake venom factor V activator (EC 3.4.21.95) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Fully activates human clotting factor V by a single cleavage at the Trp-Tyr-Leu-Arg1545-Ser-Asn-Asn-Gly bond.

This enzyme is present in venom of Daboia russelii.

References

  1. Snake venom proteases that activate blood-coagulation factor V. Methods in Enzymology. 80 Pt C. 1981. pp. 275–85. doi:10.1016/s0076-6879(81)80024-9. 
  2. "The factor V-activating enzyme (RVV-V) from Russell's viper venom. Identification of isoproteins RVV-V alpha, -V beta, and -V gamma and their complete amino acid sequences". The Journal of Biological Chemistry 263 (33): 17471–81. November 1988. PMID 3053712. 

External links