Biology:Stratum corneum chymotryptic enzyme

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Stratum corneum chymotryptic enzyme
Identifiers
EC number3.4.21.117
CAS number155215-90-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Stratum corneum chymotryptic enzyme (EC 3.4.21.117, kallikrein 7, SCCE, KLK7, PRSS6, hK7) is an enzyme.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

Cleavage of proteins with aromatic side chains in the P1 position

This enzyme has wide substrate specificity.

References

  1. ↑ "Primary substrate specificity of recombinant human stratum corneum chymotryptic enzyme". Biochemical and Biophysical Research Communications 211 (2): 586–9. June 1995. doi:10.1006/bbrc.1995.1853. PMID 7794273. 
  2. ↑ "Purification and preliminary characterization of stratum corneum chymotryptic enzyme: a proteinase that may be involved in desquamation". The Journal of Investigative Dermatology 101 (2): 200–4. August 1993. doi:10.1111/1523-1747.ep12363804. PMID 8393902. 
  3. ↑ "Cloning, expression, and characterization of stratum corneum chymotryptic enzyme. A skin-specific human serine proteinase". The Journal of Biological Chemistry 269 (30): 19420–6. July 1994. PMID 8034709. 
  4. ↑ "The KLK7 (PRSS6) gene, encoding for the stratum corneum chymotryptic enzyme is a new member of the human kallikrein gene family - genomic characterization, mapping, tissue expression and hormonal regulation". Gene 254 (1-2): 119–28. August 2000. doi:10.1016/S0378-1119(00)00280-8. PMID 10974542. 
  5. ↑ "Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis". The Journal of Investigative Dermatology 123 (1): 62–6. July 2004. doi:10.1111/j.0022-202X.2004.22708.x. PMID 15191543. 

External links



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