Chemistry:Epyrifenacil
From HandWiki
Epyrifenacil is an herbicide from the pyrimidinedione class which acts as a protoporphyrinogen oxidase inhibitor. It is effective against grass weeds and some broadleaf weeds.[1][2] It is hepatotoxic and carcinogenic in animal models but these effects are not considered likely to affect humans at relevant exposure levels.[3][4] Concerns have been raised about the environmental breakdown of epyrifenacil to the "forever chemical" trifluoroacetic acid.[5]
See also
References
- ↑ "Epyrifenacil, a new systemic PPO-inhibiting herbicide for broad-spectrum weed control". Pest Management Science 81 (5): 2463–2468. May 2025. doi:10.1002/ps.8244. PMID 38873996.
- ↑ "Recent innovations in crop protection research". Pest Management Science 81 (5): 2406–2418. May 2025. doi:10.1002/ps.8441. PMID 39344983.
- ↑ "Elucidation of the species differences of epyrifenacil-induced hepatotoxicity between mice and humans by mass spectrometry imaging analysis in chimeric mice with humanized liver". The Journal of Toxicological Sciences 46 (12): 601–609. doi:10.2131/jts.46.601. PMID 34853245.
- ↑ "Evaluation of the mode of action and human relevance of liver tumors in male mice treated with epyrifenacil". Regulatory Toxicology and Pharmacology 136. December 2022. doi:10.1016/j.yrtph.2022.105268. PMID 36210011.
- ↑ "Trump officials set to approve 'forever chemical' as pesticide ingredient.". The Guardian. 11 November 2025. https://www.theguardian.com/environment/2025/nov/11/trump-pfas-forever-chemical-pesticide.
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