Chemistry:Metanephrine

Metanephrine

Names
IUPAC name 4-(1-hydroxy-2-methylamino-ethyl)-2-methoxy-phenol
Identifiers
CAS Number	5001-33-2 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL775 Y
ChemSpider	19844 Y
IUPHAR/BPS	6644
MeSH	Metanephrine
PubChem CID	21100
UNII	1ZE0530JEJ Y
InChI InChI=1S/C10H15NO3/c1-11-6-9(13)7-3-4-8(12)10(5-7)14-2/h3-5,9,11-13H,6H2,1-2H3 Y Key: JWJCTZKFYGDABJ-UHFFFAOYSA-N Y InChI=1/C10H15NO3/c1-11-6-9(13)7-3-4-8(12)10(5-7)14-2/h3-5,9,11-13H,6H2,1-2H3 Key: JWJCTZKFYGDABJ-UHFFFAOYAB
SMILES Oc1ccc(cc1OC)C(O)CNC
Properties
Chemical formula	C10H15NO3
Molar mass	197.231 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Metanephrine, also known as metadrenaline, is a metabolite of epinephrine (also known as adrenaline) created by action of catechol-O-methyl transferase on epinephrine. An article in the Journal of the American Medical Association, 2002, indicated that the measurement of plasma free levels of the metanephrines group of molecules (including metanephrine and normetanephrine) is the best tool in the diagnosis of pheochromocytoma, an adrenal medullary neoplasm.

• 

  epinephrine

References

{{Navbox

| name = Neurotransmitter metabolism intermediates
| title = Neurotransmitter metabolic intermediates
| state = autocollapse|
| listclass = hlist

| group1 = catecholamines
  | list1 = {{Navbox|child

  | group1 = Anabolism
(tyrosine→epinephrine)
  | list1 =

• Tyrosine → Levodopa → [[Chemistry:Dop[[Chemistry:Dopamine → Norepinephrine|Norepinephrine]] → Epinephrine

  | group2 = Catabolism/
metabolites

| list2 =

dopamine:	DOPAL DOPAC MOPET Hydroxytyrosol 3-Methoxytyramine Homovanillic acid
norepinephrine:	3,4-Dihydroxymandelic acid Normetanephrine Vanillylmandelic acid 3-Methoxy-4-hydroxyphenylglycol Dihydroxyphenylethylene glycol
epinephrine:	Metanephrine

}} 

| group3 = tryptophan→serotonin

| list3 =

anabolism:	5-Hydroxytryptophan
catabolism:	5-Hydroxyindoleacetic acid

| group4 = serotonin→melatonin
| list4 =

• Normelatonin

}}