Chemistry:Oroxindin

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Oroxindin is a flavone, a type of phenolic chemical compound. It is a wogonoside, more accurately a wogonin glucuronide isolated from Oroxylum indicum (Bignoniaceae),[1] Bacopa monnieri (Plantaginaceae), and Holmskioldia sanguinea (Chinese hat plant, Verbenaceae).[2]

Formation

A glucuronosyltransferase anzyme converts wogonin to its glucuronide by adding a sugar acid to one of the phenolic hydroxy group, with uridine diphosphate (UDP) as byproduct:[3]

  1. REDIRECT Template:Chemical reaction

References

  1. Ramachandran Nair, A. G.; Joshi, B. S. (1979). "Oroxindin—A new flavone glucuronide from Oroxylum indicum Vent". Proceedings / Indian Academy of Sciences 88 (5): 323–327. doi:10.1007/BF02844710. 
  2. Chaudhuri, P. K.; Srivastava, Rashmi; Kumar, Sunil; Kumar, Sushil (2004). "Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea". Phytotherapy Research 18 (2): 114–117. doi:10.1002/ptr.1278. 
  3. Hădărugă, Daniel-Ioan; Hădărugă, Nicoleta-Gabriela (2023). "Flavones: Structure, Properties, Sources and Food Applications". Handbook of Food Bioactive Ingredients. pp. 111–158. doi:10.1007/978-3-031-28109-9_4. ISBN 978-3-031-28108-2.