Chemistry:6-Hydroxyflavone
From HandWiki
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| Names | |
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| IUPAC name
6-Hydroxyflavone
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| Systematic IUPAC name
6-Hydroxy-2-phenyl-4H-1-benzopyran-4-one | |
| Other names
6-Monohydroxyflavone; 6-Hydroxy-2-phenyl-4-benzopyrone
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3D model (JSmol)
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| Properties | |
| C15H10O3 | |
| Molar mass | 238.242 g·mol−1 |
| Melting point | 234 to 236 °C (453 to 457 °F; 507 to 509 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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Tracking categories (test):
6-Hydroxyflavone is a flavone, a type of chemical compound. It is one of the noncompetitive inhibitors of cytochrome P450 2C9. It is reported in Crocus and leaves of Barleria prionitis Linn. (a common Acanthaceae from India).[1] 6-Hydroxyflavone may have a potential as a therapeutic drug capable for the treatment of anxiety-like disorders. Compared to the full agonist diazepam, 6-HydroxyFlavone was approximately 200x less potent.[2][3]
References
- ↑ M Daniel (2006). Medicinal Plants: Chemistry and Properties. Science Publishers. p. 78. ISBN 978-1-57808-395-4. https://books.google.com/books?id=5sU6yo1jFxQC&pg=PA78.
- ↑ Ren, Lihuan; Wang, Feng; Xu, Zhiwen; Chan, Wing Man; Zhao, Cunyou; Xue, Hong (2010), "GABAA receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone", Biochemical Pharmacology 79 (9): 1337–1344, doi:10.1016/j.bcp.2009.12.024, PMID 20067772
- ↑ "6-HYDROXYFLAVONE | CAS:6665-83-4 | Huateng Pharma | Pharmaceutical chemical reagents, PEG derivatives". http://en.huatengsci.com/product/6-HYDROXYFLAVONE.html.
External links
- 6-hydroxy flavone on Plant Metabolic Network
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