Chemistry:Oxidized cellulose

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Oxidized cellulose
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Oxidized cellulose is a water-insoluble derivative of cellulose. It can be produced from cellulose by the action of an oxidizing agent, such as chlorine, hydrogen peroxide, peracetic acid, chlorine dioxide, nitrogen dioxide, persulfates, permanganate, dichromate-sulfuric acid, hypochlorous acid, hypohalites or periodates and a variety of metal catalysts.[1] Oxidized cellulose may contain carboxylic acid, aldehyde, and/or ketone groups, in addition to the original hydroxyl groups of the starting material, cellulose, depending on the nature of the oxidant and reaction conditions.[2]

It is an antihemorrhagic.[3] It works both by absorbing the blood (similar to a cotton ball)[4] and by triggering the contact activation system. It is poorly absorbed and may cause healing complications postoperatively.[5]

See also

References

  1. "The catalytic oxidation of biomass to new materials focusing on starch, cellulose and lignin.". Coordination Chemistry Reviews 254 (15–16): 1854–1870. August 2010. doi:10.1016/j.ccr.2010.04.007. http://oro.open.ac.uk/31289/19/Catalytic_oxidation_of_biomass_to_new_materials.pdf. 
  2. Banker GS, Kumar V, "Oxidized cellulose", US patent 5780618, issued 14 July 1998
  3. "MR characteristics of oxidized cellulose (Surgicel)". AJR. American Journal of Roentgenology 172 (6): 1481–1484. June 1999. doi:10.2214/ajr.172.6.10350276. PMID 10350276. 
  4. "Oxidised Cellulose". 30 November 2023. https://www.admedsol.com/our-technologies/oxidised-cellulose. 
  5. "Intraoperative Complications". Misch's Avoiding Complications in Oral Implantology. 2018. pp. 267–293. doi:10.1016/B978-0-323-37580-1.00007-X. ISBN 978-0-323-37580-1.