Chemistry:Lusutrombopag
From HandWiki
Short description: Chemical compound
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| Pronunciation | loo" soo trom' boe pag |
| Trade names | Mulpleta, Mulpleo |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a618043 |
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| Routes of administration | By mouth |
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| Formula | C29H32Cl2N2O5S |
| Molar mass | 591.54 g·mol−1 |
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Lusutrombopag, sold under the brand name Mulpleta among others, is a medication that has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts) such as thrombocytopenia associated with chronic liver disease in patients prior to elective invasive procedures.[1] It is being manufactured and marketed in Japan by Shionogi.[2][3][4] It was approved by the U.S. Food and Drug Administration (FDA) in July 2018, and NICE in January 2020.[5][6]
It was approved for medical use in the European Union in February 2019.[7]
References
- ↑ "Lusutrombopag: A Review in Thrombocytopenia in Patients with Chronic Liver Disease Prior to a Scheduled Procedure". Drugs 79 (15): 1689–1695. October 2019. doi:10.1007/s40265-019-01197-8. PMID 31529283.
- ↑ Shionogi Receives Marketing and Manufacturing Approval in Japan for Mulpleta Tablets 3mg for Improvement of Thrombocytopenia, September 28, 2015
- ↑ Shionogi Launches Mulpleta Tablets 3mg In Japan for Improvement of Thrombocytopenia
- ↑ Lusutrombopag (Mulpleta) for severe thrombocytopenia in patients with chronic liver disease undergoing an elective invasive procedure
- ↑ "FDA approves lusutrombopag for thrombocytopenia in adults with chronic liver disease". U.S. Food and Drug Administration (FDA). July 31, 2018. https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-lusutrombopag-thrombocytopenia-adults-chronic-liver-disease.
- ↑ "Overview | Lusutrombopag for treating thrombocytopenia in people with chronic liver disease needing a planned invasive procedure | Guidance | NICE". https://www.nice.org.uk/guidance/ta617.
- ↑ "Mulpleo EPAR". https://www.ema.europa.eu/en/medicines/human/EPAR/mulpleo.
External links
- "Lusutrombopag". Drug Information Portal. U.S. National Library of Medicine. https://druginfo.nlm.nih.gov/drugportal/name/lusutrombopag.
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