Chemistry:Secnidazole
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Short description: Chemical compound
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Trade names | Solosec |
Other names | PM 185184, RP 14539 |
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Routes of administration | Oral |
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Formula | C7H11N3O3 |
Molar mass | 185.183 g·mol−1 |
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Secnidazole (trade names Flagentyl, Sindose, Secnil, Solosec) is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported.[1] It has also been tested against Atopobium vaginae.[2]
In the United States, secnidazole is FDA approved for the treatment of bacterial vaginosis and trichomoniasis in adult women.[3]
References
- ↑ "Dientamoeba fragilis, a neglected cause of diarrhea, successfully treated with secnidazole". Clinical Microbiology and Infection 9 (2): 110–3. February 2003. doi:10.1046/j.1469-0691.2003.00504.x. PMID 12588330.
- ↑ "In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis". Clinical Microbiology and Infection 16 (5): 470–2. May 2010. doi:10.1111/j.1469-0691.2009.02852.x. PMID 19548924.
- ↑ "Secnidazole for Trichomoniasis in Women and Men". Sex Med Rev 10 (2): 255–262. April 2022. doi:10.1016/j.sxmr.2021.12.004. PMID 35153156.
Further reading
- "Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis". Drugs 51 (4): 621–38. April 1996. doi:10.2165/00003495-199651040-00007. PMID 8706597.
Original source: https://en.wikipedia.org/wiki/Secnidazole.
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