Medicine:Inference-based therapy

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Short description: Treatment for OCD

Inference-based therapy (IBT), also known as inference-based cognitive behavioral therapy (I-CBT),[1] originated as a form of cognitive therapy developed for treating obsessive-compulsive disorder.[2] IBT followed the observation that people with OCD often inferred danger on the basis of inverse inference (inferring reality from hypothetical premises).[3][4] Later the model was extended to inferential confusion, where inverse inference leads to distrust of the senses and investment in remote possibility.[5] In this model, individuals with obsessive-compulsive disorder are hypothesized to put a greater emphasis on an imagined possibility than on what can be perceived with the senses, and to confuse the imagined possibility with reality (inferential confusion).[5] According to inference-based therapy, obsessional thinking occurs when the person replaces reality and real probabilities with imagined possibilities; the obsession is hypothesized to concern a doubt about a possible state of affairs.[6]

According to inference-based therapy, individuals with obsessive-compulsive disorder attempt to resolve the doubt by modifying reality (via compulsions and neutralizations) which merely increase the imaginary pathological doubt rather than resolve it since reality is not the problem.[7] Obsessions are hypothesized to begin with the initial doubt (“Maybe I could be dirty”) which is not a normal intrusion but a sign that the person is already in obsessional thinking.[8]

Inference-based therapy hypothesizes that the doubt and investment in possibilities leave the person vulnerable to spiral into further imagined connections and dissociative absorption in what could further transpire.[8]

History

Inference-based therapy was developed in the late 1990s for treating obsessive-compulsive disorder.[3][4] Initially, the model was developed mostly for obsessive-compulsive disorder with overt compulsions and for individuals presenting obsessive-compulsive disorder with overvalued ideas (i.e., obsessions with a bizarre content and strongly invested by the individual, such as feeling dirty after seeing a dirty person), given that the model revolves around the imaginative, often idiosyncratic nature of the obsession.[9] The model was expanded to all types of obsessions and compulsions. Inference-based therapy is now applied to anyone of the OCD spectrum disorder and believed to be applicable to other disorders as well.[10]

Theoretical model

According to inference-based therapy, obsessional doubt (obsessions) result from a narrative constituted by a specific inductive-reasoning style characterized by a distrust of the senses and an overinvestment in remote possibilities.[11] Individuals become absorbed in an imagined possibility forming the obsessional doubt (“perhaps my hands are dirty”) at the expense of what can be perceived with the senses in the here and now (“my eyes tell me that hands are clean”). The imagined possibility seems so credible that individuals live this possibility as if it were true, and experience physiological reactions, feelings of anxiety, and compulsions that are congruent with the imagined scenario and become immersed in the obsessional doubt.[5] According to inference-based therapy, individuals are more prone to experience specific obsessions in some and not other areas because the content reflects an underlying vulnerable self-theme (e.g., “I might be the type of person who is neglectful”).[12]

Treatment

The goal of inference-based therapy is to reorient clients towards trusting the senses and relating to reality in a normal, non-effortful way.[2] [11]Differences between normal and obsessional doubts are presented, and clients are encouraged to use their senses and reasoning as they do in non-obsessive-compulsive disorder situations. The exact moment where client cross over from reality to a possibility is identified, and clients are invited to go back to reality, use their senses, and tolerate the void of trusting the senses rather than enacting compulsive behaviors.

Empirical support

There is some empirical support for main premises of inference-based therapy regarding the role of inductive reasoning processes, the imagination, and inferential confusion.[13] There is also evidence for the efficacy of inference-based therapy for obsessive-compulsive disorder.[14][15][16][17][18]

References

  1. ↑ Aardema, Frederick; Bouchard, Stéphane; Koszycki, Diana; Lavoie, Marc E.; Audet, Jean-Sebastien; O’Connor, Kieron (2022). "Evaluation of Inference-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder: A Multicenter Randomized Controlled Trial with Three Treatment Modalities" (in en). Psychotherapy and Psychosomatics 91 (5): 348–359. doi:10.1159/000524425. ISSN 0033-3190. https://www.karger.com/Article/FullText/524425. 
  2. ↑ 2.0 2.1 O'Connor, Kieron Philip; Aardema, Frederick; Pélissier, Marie-Claude (2005). Beyond reasonable doubt: reasoning processes in obsessive-compulsive disorder and related disorders (Repr ed.). Chichester: Wiley. ISBN 978-0-470-86877-5. 
  3. ↑ 3.0 3.1 O'Connor, Kieron; Robillard, Sophie (1995). "Inference processes in Obsessive-Compulsive Disorder: Some clinical observations" (in en). Behaviour Research and Therapy 33 (8): 887–896. doi:10.1016/0005-7967(95)00042-V. https://linkinghub.elsevier.com/retrieve/pii/000579679500042V. 
  4. ↑ 4.0 4.1 O’Connor, Kieron; Robillard, Sophie (1999). "A Cognitive Approach to the Treatment of Primary Inferences in Obsessive-Compulsive Disorder" (in en). Journal of Cognitive Psychotherapy 13 (4): 359–375. doi:10.1891/0889-8391.13.4.359. ISSN 0889-8391. http://connect.springerpub.com/lookup/doi/10.1891/0889-8391.13.4.359. 
  5. ↑ 5.0 5.1 5.2 Aardema, Frederick; O’Connor, Kieron P.; Emmelkamp, Paul M.G.; Marchand, André; Todorov, Christo (2005). "Inferential confusion in obsessive–compulsive disorder: the inferential confusion questionnaire" (in en). Behaviour Research and Therapy 43 (3): 293–308. doi:10.1016/j.brat.2004.02.003. https://linkinghub.elsevier.com/retrieve/pii/S0005796704000683. 
  6. ↑ O'Connor, Kieron (2002). "Intrusions and inferences in obsessive compulsive disorder" (in en). Clinical Psychology & Psychotherapy 9 (1): 38–46. doi:10.1002/cpp.303. ISSN 1063-3995. https://onlinelibrary.wiley.com/doi/10.1002/cpp.303. 
  7. ↑ O'Connor, Kieron; Aardema, Frederick (2003). "Fusion or Confusion in Obsessive-Compulsive Disorder" (in en). Psychological Reports 93 (1): 227–232. doi:10.2466/pr0.2003.93.1.227. ISSN 0033-2941. http://journals.sagepub.com/doi/10.2466/pr0.2003.93.1.227. 
  8. ↑ 8.0 8.1 O'Connor, Kieron; Aardema, Frederick (2011-11-25) (in en). Clinician's Handbook for Obsessive‐Compulsive Disorder: Inference‐Based Therapy (1 ed.). Wiley. doi:10.1002/9781119960027. ISBN 978-0-470-68409-2. https://onlinelibrary.wiley.com/doi/book/10.1002/9781119960027. 
  9. ↑ Aardema, Frederick; Emmelkamp, Paul M. G.; O'Connor, Kieron P. (2005). "Inferential confusion, cognitive change and treatment outcome in Obsessive-Compulsive Disorder" (in en). Clinical Psychology & Psychotherapy 12 (5): 337–345. doi:10.1002/cpp.464. ISSN 1063-3995. https://onlinelibrary.wiley.com/doi/10.1002/cpp.464. 
  10. ↑ O'Connor, Kieron; Koszegi, Natalia; Aardema, Frederick; van Niekerk, Jan; Taillon, Annie (2009). "An Inference-Based Approach to Treating Obsessive-Compulsive Disorders" (in en). Cognitive and Behavioral Practice 16 (4): 420–429. doi:10.1016/j.cbpra.2009.05.001. https://linkinghub.elsevier.com/retrieve/pii/S1077722909000947. 
  11. ↑ 11.0 11.1 O'Connor, Kieron; Aardema, Frederick (2011-11-25) (in en). Clinician's Handbook for Obsessive‐Compulsive Disorder: Inference‐Based Therapy (1 ed.). Wiley. doi:10.1002/9781119960027. ISBN 978-0-470-68409-2. https://onlinelibrary.wiley.com/doi/book/10.1002/9781119960027. 
  12. ↑ Aardema, Frederick; O’Connor, Kieron (2007). "The Menace Within: Obsessions and the Self" (in en). Journal of Cognitive Psychotherapy 21 (3): 182–197. doi:10.1891/088983907781494573. ISSN 0889-8391. http://connect.springerpub.com/lookup/doi/10.1891/088983907781494573. 
  13. ↑ Julien, Dominic; O’Connor, Kieron; Aardema, Frederick (2016). "The inference-based approach to obsessive-compulsive disorder: A comprehensive review of its etiological model, treatment efficacy, and model of change" (in en). Journal of Affective Disorders 202: 187–196. doi:10.1016/j.jad.2016.05.060. https://linkinghub.elsevier.com/retrieve/pii/S0165032716302130. 
  14. ↑ Aardema, Frederick; O'Connor, Kieron (2012). "Dissolving the tenacity of obsessional doubt: Implications for treatment outcome" (in en). Journal of Behavior Therapy and Experimental Psychiatry 43 (2): 855–861. doi:10.1016/j.jbtep.2011.12.006. https://linkinghub.elsevier.com/retrieve/pii/S0005791611001315. 
  15. ↑ Aardema, Frederick; Wu, Kevin D.; Careau, Yves; O’Connor, Kieron; Julien, Dominic; Dennie, Susan (2010). "The Expanded Version of the Inferential Confusion Questionnaire: Further Development and Validation in Clinical and Non-Clinical Samples" (in en). Journal of Psychopathology and Behavioral Assessment 32 (3): 448–462. doi:10.1007/s10862-009-9157-x. ISSN 0882-2689. http://link.springer.com/10.1007/s10862-009-9157-x. 
  16. ↑ Del Borrello, Loide; O'Connor, Kieron (2014). "The Role of Obsessive Beliefs and Inferential Confusion in Predicting Treatment Outcomes for Different Subtypes of Obsessive-Compulsive Disorder" (in en). International Journal of Cognitive Therapy 7 (1): 43–66. doi:10.1521/ijct.2014.7.1.43. ISSN 1937-1209. http://guilfordjournals.com/doi/10.1521/ijct.2014.7.1.43. 
  17. ↑ O'Connor, K. P.; Aardema, F.; Bouthillier, D.; Fournier, S.; Guay, S.; Robillard, S.; Pélissier, M. C.; Landry, P. et al. (2005-09-05). "Evaluation of an Inference‐Based Approach to Treating Obsessive‐Compulsive Disorder" (in en). Cognitive Behaviour Therapy 34 (3): 148–163. doi:10.1080/16506070510041211. ISSN 1650-6073. http://www.tandfonline.com/doi/abs/10.1080/16506070510041211. 
  18. ↑ Visser, Henny A.; van Megen, Harold; van Oppen, Patricia; Eikelenboom, Merijn; Hoogendorn, Adriaan W.; Kaarsemaker, Maarten; van Balkom, Anton J. (2015). "Inference-Based Approach versus Cognitive Behavioral Therapy in the Treatment of Obsessive-Compulsive Disorder with Poor Insight: A 24-Session Randomized Controlled Trial" (in en). Psychotherapy and Psychosomatics 84 (5): 284–293. doi:10.1159/000382131. ISSN 0033-3190. https://www.karger.com/Article/FullText/382131. 



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