Biology:2-nitroimidazole nitrohydrolase

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Short description: Class of enzymes
2-nitroimidazole nitrohydrolase
Identifiers
EC number3.5.99.9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

2-nitroimidazole nitrohydrolase (EC 3.5.99.9, NnhA, 2NI nitrohydrolase, 2NI denitrase) is an enzyme with systematic name 2-nitroimidazole nitrohydrolase.[1] This enzyme catalyses the following chemical reaction

2-nitroimidazole + H2O [math]\displaystyle{ \rightleftharpoons }[/math] imidazol-2-one + nitrite

This enzyme is present in the soil bacterium Mycobacterium sp. JS330

References

  1. "Catabolic pathway for 2-nitroimidazole involves a novel nitrohydrolase that also confers drug resistance". Environmental Microbiology 13 (4): 1010–7. April 2011. doi:10.1111/j.1462-2920.2010.02406.x. PMID 21244596. 

External links