Biology:Alternansucrase
Alternansucrase | |||||||||
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![]() Alternansucrase (dextransucrase) monomer, Leuconostoc citreum | |||||||||
Identifiers | |||||||||
EC number | 2.4.1.140 | ||||||||
CAS number | 100630-46-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, an alternansucrase (EC 2.4.1.140) is an enzyme that catalyzes a chemical reaction that transfers an alpha-D-glucosyl residue from sucrose alternately to the 6- and 3-positions of the non-reducing terminal residue of an alpha-D-glucan, thereby creating a glucan with alternating alpha-1,6- and alpha-1,3-bonds. The name "alternan" was coined in 1982 (Cote & Robyt) for the glucan based on its alternating linkage structure.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:1,6(1,3)-alpha-D-glucan 6(3)-alpha-D-glucosyltransferase. Other names in common use include sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase, sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and, and 6-alpha-D-glucosyltransferase.
References
- "Isolation and partial characterization of an extracellular glucansucrase from Leuconostoc mesenteroides NRRL B-1355 that synthesizes an alternating (1→6), (1→3)-α-D-glucan". Carbohydr. Res. 101 (1): 57–74. 1982. doi:10.1016/S0008-6215(00)80795-8. PMID 7060056.
![]() | Original source: https://en.wikipedia.org/wiki/Alternansucrase.
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