Biology:Methylenediurea deaminase
From HandWiki
| Methylenediurea deaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.5.3.21 | ||||||||
| CAS number | 205830-62-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Methylenediurea deaminase (EC 3.5.3.21, methylenediurease) is an enzyme with systematic name methylenediurea aminohydrolase found in Brucella anthropi, a bacterium.[1] This enzyme catalyses the following chemical reaction:
- methylenediurea + 2 H2O [math]\displaystyle{ \rightleftharpoons }[/math] N-(hydroxymethyl)urea + 2 NH3 + CO2 (overall reaction)
- (1a) methylenediurea + H2O [math]\displaystyle{ \rightleftharpoons }[/math] N-(carboxyaminomethyl)urea + NH3
- (1b) N-(carboxyaminomethyl)urea [math]\displaystyle{ \rightleftharpoons }[/math] N-(aminomethyl)urea + CO2 (spontaneous)
- (1c) N-(aminomethyl)urea + H2O [math]\displaystyle{ \rightleftharpoons }[/math] N-(hydroxymethyl)urea + NH3 (spontaneous)
Methylenediurea is hydrolysed and decarboxylated to give an aminated methylurea.
References
- ↑ "Purification and characterisation of an enzyme from a strain of Ochrobactrum anthroπ that degrades condensation products of urea and formaldehyde (ureaform)". Canadian Journal of Microbiology 43: 1111–1117. 1997. doi:10.1139/m97-159.
External links
- Methylenediurea+deaminase at the US National Library of Medicine Medical Subject Headings (MeSH)
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