Biology:LCOR
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Ligand-dependent corepressor is a protein that in humans is encoded by the LCOR gene.[1][2][3]
Function
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box.[3]
References
- ↑ "Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms". Mol Cell 11 (1): 139–50. Jan 2003. doi:10.1016/S1097-2765(03)00014-5. PMID 12535528.
- ↑ "Corepressor recruitment by agonist-bound nuclear receptors". Vitam Horm. Vitamins & Hormones 68: 123–43. Jun 2004. doi:10.1016/S0083-6729(04)68004-6. ISBN 9780127098685. PMID 15193453.
- ↑ 3.0 3.1 "Entrez Gene: LCOR ligand dependent nuclear receptor corepressor". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84458.
Further reading
- "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 8 (2): 85–95. 2001. doi:10.1093/dnares/8.2.85. PMID 11347906.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1).". FEBS Lett. 535 (1–3): 61–5. 2003. doi:10.1016/S0014-5793(02)03858-9. PMID 12560079.
- "Coordinated histone modifications mediated by a CtBP co-repressor complex". Nature 422 (6933): 735–8. 2003. doi:10.1038/nature01550. PMID 12700765.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The DNA sequence and comparative analysis of human chromosome 10". Nature 429 (6990): 375–81. 2004. doi:10.1038/nature02462. PMID 15164054. Bibcode: 2004Natur.429..375D.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Ligand-dependent corepressor
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