Biology:8-oxoguanine deaminase

From HandWiki
Short description: Class of enzymes
8-oxoguanine deaminase
Identifiers
EC number3.5.4.32
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

8-oxoguanine deaminase (EC 3.5.4.32, 8-OGD) is an enzyme with systematic name 8-oxoguanine aminohydrolase.[1] This enzyme catalyses the following chemical reaction

8-oxoguanine + H2O [math]\displaystyle{ \rightleftharpoons }[/math] urate + NH3

Zn2+ is bound in the active site.

References

  1. "The hunt for 8-oxoguanine deaminase". Journal of the American Chemical Society 132 (6): 1762–3. February 2010. doi:10.1021/ja909817d. PMID 20088583. 

External links