Biology:Adamalysin

From HandWiki
Short description: Class of enzymes
Adamalysin
Identifiers
EC number3.4.24.46
CAS number74812-51-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Adamalysin (EC 3.4.24.46, Crotalus adamanteus metalloendopeptidase, proteinase I and II, Crotalus adamanteus venom proteinase II, adamalysin II) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of Phe1-Val, His5-Leu, His10-Leu, Ala14-Leu, Leu15-Tyr, and Tyr16-Leu of insulin B chain

This enzyme is present in the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).

See also

  • A disintegrin and metalloproteinase

References

  1. "Purification and some properties of two proteinases from Crotalus adamanteus venom that inactivate human alpha 1-proteinase inhibitor". The Journal of Biological Chemistry 253 (22): 8340–5. November 1978. PMID 309470. 

External links