Biology:Alcohol dehydrogenase (azurin)
From HandWiki
| Alcohol dehydrogenase (azurin) | |||||||||
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| Identifiers | |||||||||
| EC number | 1.1.9.1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Alcohol dehydrogenase (azurin) (EC 1.1.9.1, type II quinoprotein alcohol dehydrogenase, quinohaemoprotein ethanol dehydrogenase, QHEDH, ADHIIB) is an enzyme with systematic name alcohol:azurin oxidoreductase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- primary alcohol + azurin [math]\displaystyle{ \rightleftharpoons }[/math] aldehyde + reduced azurin
This enzyme is a periplasmic PQQ-containing quinohemoprotein.
References
- ↑ "Quinohaemoprotein alcohol dehydrogenase apoenzyme from Pseudomonas testosteroni". The Biochemical Journal 234 (3): 611–5. March 1986. doi:10.1042/bj2340611. PMID 3521592.
- ↑ "Characterization of the interaction between PQQ and heme c in the quinohemoprotein ethanol dehydrogenase from Comamonas testosteroni". Biochemistry 34 (29): 9451–8. July 1995. doi:10.1021/bi00029a021. PMID 7626615.
- ↑ "Three distinct quinoprotein alcohol dehydrogenases are expressed when Pseudomonas putida is grown on different alcohols". Journal of Bacteriology 177 (9): 2442–50. May 1995. doi:10.1128/jb.177.9.2442-2450.1995. PMID 7730276.
- ↑ "Electron transfer from quinohemoprotein alcohol dehydrogenase to blue copper protein azurin in the alcohol oxidase respiratory chain of Pseudomonas putida HK5". Biochemistry 38 (19): 6111–8. May 1999. doi:10.1021/bi990121f. PMID 10320337.
- ↑ "Structure at 1.9 A resolution of a quinohemoprotein alcohol dehydrogenase from Pseudomonas putida HK5". Structure 10 (6): 837–49. June 2002. doi:10.1016/s0969-2126(02)00774-8. PMID 12057198.
- ↑ "Crystal structure of quinohemoprotein alcohol dehydrogenase from Comamonas testosteroni: structural basis for substrate oxidation and electron transfer". The Journal of Biological Chemistry 277 (5): 3727–32. February 2002. doi:10.1074/jbc.M109403200. PMID 11714714.
External links
- Alcohol+dehydrogenase+(azurin) at the US National Library of Medicine Medical Subject Headings (MeSH)
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