Biology:Amycolatopsis

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Amycolatopsis is a genus of high GC-content bacteria within the family Pseudonocardiaceae.[1] The genus is known for producing many types of antibiotics, including

  • Epoxyquinomicin, related to Amycolatopsis sulphurea, are a class of weak antibiotic and anti-inflammatory agent.[2]
  • Vancomycin, obtained from Amycolatopsis orientalis, is being used for infections resistant to other antibiotics.
  • Ristocetin, made by Amycolatopsis lurida, was an antibiotic but ceased to apply due to adverse effects of platelet agglutination. Now it is used to assay von Willebrand disease.

Degradation of bio-polymers

Several bacteria from the genus Amycolatopsis are able to enzymatically hydrolyze the ester bonds of poly-lactic acid (PLA) films in aquatic medium. So far, it is one of the few known bacteria able to biodegrade the bioplastic outside compost facilities in a relatively short period of time.[3][4]

Phylogeny

The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN)[5] and National Center for Biotechnology Information (NCBI).[6]

16S rRNA based LTP_10_2024[7][8][9]
Amycolatopsis

A. acididurans Teo et al. 2021

A. alkalitolerans Narsing Rao et al. 2020

A. pithecellobii corrig. Mingma et al. 2020

A. pigmentata Tamura et al. 2010

A. helveola Tamura et al. 2010

A. taiwanensis Tseng et al. 2006

A. cappadoca Işık et al. 2019

A. thermalba Zucchi et al. 2012

A. ruanii Zucchi et al. 2012

A. granulosa Zucchi et al. 2012

A. viridis Zucchi et al. 2012

A. methanolica De Boer et al. 1990

A. thermoflava Chun et al. 1999

A. tucumanensis Albarracín et al. 2010

A. eurytherma Kim et al. 2002

A. thermophila Zucchi et al. 2012

A. deserti Busarakam et al. 2017

A. endophytica Miao et al. 2012

A. acidicola Teo et al. 2020

A. halophila Tang et al. 2010

A. salitolerans Guan et al. 2012

A. acidiphila Oyuntsetseg et al. 2017

A. bartoniae Zucchi et al. 2012

A. rhizosphaerae Thawai 2018

A. dongchuanensis Nie et al. 2012

A. sacchari Goodfellow et al. 2001

A. albispora Zhang et al. 2016

A. magusensis Camas et al. 2013

A. xuchangensis Huang et al. 2021

A. marina Bian et al. 2009

A. palatopharyngis Huang et al. 2004

A. xylanica Chen et al. 2010

A. suaedae Chantavorakit et al. 2019

"A. aidingensis" Li et al. 2021

A. cihanbeyliensis Tatar et al. 2013

A. anabasis Wang et al. 2020

A. minnesotensis Lee et al. 2006

A. nigrescens Groth et al. 2007

A. antarctica Wang et al. 2018

A. jiguanensis Huang et al. 2021

A. jiangsuensis Xing et al. 2014[10]

A. panacis Peng et al. 2019

A. ultiminotia Lee 2009

A. jejuensis Lee 2006

A. sulphurea Lechevalier et al. 1986

A. dendrobii Tedsree et al. 2021

A. nivea Niu et al. 2020

A. saalfeldensis Carlsohn et al. 2007

A. alba Mertz and Yao 1993

A. thailandensis Chomchoei et al. 2011

A. umgeniensis Everest et al. 2013[11]

A. coloradensis Labeda 1995

A. roodepoortensis Everest et al. 2015

A. orientalis (Pittenger and Brigham 1956) Lechevalier et al. 1986

A. regifaucium Tan et al. 2007

A. speibonae Everest et al. 2015

A. decaplanina Wink et al. 2004

A. keratiniphila Al-Musallam et al. 2003

A. lurida (Lechevalier et al. 1986) Stackebrandt et al. 2004

A. azurea (Ōmura et al. 1983) Henssen et al. 1987

A. japonica corrig. Goodfellow et al. 1997

A. oliviviridis Penkhrue et al. 2018

A. iheyensis Ngamcharungchit et al. 2023

A. rhabdoformis Souza et al. 2015

A. australiensis Tan et al. 2006

A. plumensis Saintpierre-Bonaccio et al. 2005

A. tolypomycina Wink et al. 2003

A. albidoflava corrig. Lee and Hah 2001

A. halotolerans Lee 2006

A. echigonensis Ding et al. 2007

A. niigatensis Ding et al. 2007

A. benzoatilytica Majumdar et al. 2006

A. circi Everest and Meyers 2012

A. equina Everest and Meyers 2012

A. hippodromi Everest and Meyers 2012

A. rubida Huang et al. 2001

A. silviterrae Jamjan et al. 2018

A. bullii Zucchi et al. 2012

A. vancoresmycina Wink et al. 2003

A. kentuckyensis Labeda et al. 2003

A. lexingtonensis Labeda et al. 2003

A. pretoriensis Labeda et al. 2003

A. rifamycinica Bala et al. 2004

A. eburnea Chaiya et al. 2019

"A. camponoti" Zakalyukina et al. 2022

A. balhimycina Wink et al. 2003

A. samaneae Duangmal et al. 2011

A. stemonae Klykleung et al. 2015

A. mediterranei (Margalith and Beretta 1960) Lechevalier et al. 1986

A. vastitatis Idris et al. 2019

File:Amycolatopsis bartoniae NRRL B-24846 (Type Strain).jpg
Amycolatopsis bartoniae

Species incertae sedis:

  • A. arida Nouioui et al. 2018
  • A. carbonis Oyuntsetseg and Kim 2024
  • "A. cyclosori" Chen et al. 2025
  • "A. cynarae" Deng et al. 2024
  • "A. flava" Wei et al. 2015
  • "A. lactamdurans" Stapley et al. 1973 ex Barreiro et al. 2000
  • A. nalaikhensis Oyuntsetseg & Kim 2024
  • "A. pittospori" Kaewkla and Franco 2021
  • A. ponsaeliensis Thompson et al. 2025
  • A. rhizosphaerihabitans Chen et al. 2025

See also

References

  1. Cite error: Invalid <ref> tag; no text was provided for refs named Lechevalier
  2. NAOKI, MATSUMOTO (November 1997). "Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities.". J Antibiot (Tokyo) 50 (11): 900–905. doi:10.7164/antibiotics.50.900. PMID 9592560. 
  3. Poly(lactic acid) : synthesis, structures, properties, processing, and applications. Auras, Rafael.. Hoboken, N.J.: Wiley. 2010. ISBN 978-0-470-64983-1. OCLC 709664760. 
  4. Y. Ikura, T. Kudo (1999). "Isolation of a microorganism capable of degrading poly-(L-lactide)". J. Gen. Appl. Microbiol. 45 (5): 247–251. doi:10.2323/jgam.45.247. PMID 12501367. 
  5. Amycolatopsis in LPSN; Freese, H. M.; Meier-Kolthoff, J. P.; Sardà Carbasse, J.; Afolayan, A. O.; Göker, M. (29 October 2025). "TYGS and LPSN in 2025: a Global Core Biodata Resource for genome-based classification and nomenclature of prokaryotes within DSMZ Digital Diversity". Nucleic Acids Research 53: D1–D12. doi:10.1093/nar/gkaf1110. 
  6. C.L. Schoch. "Amycolatopsis". National Center for Biotechnology Information (NCBI) taxonomy database. https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?command=show&mode=tree&id=1813&lvl=3. 
  7. "The LTP". https://imedea.uib-csic.es/mmg/ltp/#LTP. 
  8. "LTP_all tree in newick format". https://imedea.uib-csic.es/mmg/ltp/wp-content/uploads/ltp/LTP_all_10_2024.ntree. 
  9. "LTP_10_2024 Release Notes". https://imedea.uib-csic.es/mmg/ltp/wp-content/uploads/ltp/LTP_10_2024_release_notes.pdf. 
  10. Xing, Ke; Liu, Wei; Zhang, Yue-Ji; Bian, Guang-Kai; Zhang, Wen-Di; Tamura, Tomohiko; Lee, Jung-Sook; Qin, Sheng et al. (2013). "Amycolatopsis jiangsuensis sp. nov., a novel endophytic actinomycete isolated from a coastal plant in Jiangsu, China". Antonie van Leeuwenhoek 103 (2): 433–439. doi:10.1007/s10482-012-9823-y. PMID 23053697. 
  11. Everest, Gareth J.; Roes-Hill, Marilize le; Omorogie, Clifford; Cheung, Shuk-Kwan; Cook, Andrew E.; Goodwin, Candice M.; Meyers, Paul R. (2013). "Amycolatopsis umgeniensis sp. nov., isolated from soil from the banks of the Umgeni River in South Africa". Antonie van Leeuwenhoek 103 (3): 673–681. doi:10.1007/s10482-012-9851-7. PMID 23180373. 

Wikidata ☰ Q481996 entry