Biology:Haplogroup IWX (mtDNA)
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In human genetics, Haplogroup IWX was a human mitochondrial DNA (mtDNA) haplogroup.[1][2] It was thought to cluster haplogroups I, W, and X.[3][4] Studies suggested haplogroup IWX to be highly protective against AIDS progression.[5] It is now known that Haplogroup I is descendant of Haplogroup N1. It has also been proposed that Haplogroup W be placed as a descendant of Haplogroup N2b.[6]
References
- ↑ "Mitochondrial haplogroup H and Alzheimer's disease--is there a connection?". Neurobiology of Aging 30 (11): 1749–55. November 2009. doi:10.1016/j.neurobiolaging.2008.01.004. PMID 18308428.
- ↑ The genome of Homo sapiens
- ↑ "[Diversity of mitochondrial DNA haplotypes in ethnic populations of the Volga-Ural region of Russia"] (in Russian). Molekuliarnaia Biologiia 36 (6): 990–1001. 2002. PMID 12500536. http://evolutsioon.ut.ee/publications/Bermisheva2002.pdf.
- ↑ "Geographic patterns of mtDNA diversity in Europe". American Journal of Human Genetics 66 (1): 262–78. January 2000. doi:10.1086/302706. PMID 10631156. PMC 1288355. http://web.unife.it/progetti/genetica/Guido/pdf/11.pdf. Retrieved 2008-12-08.
- ↑ "Mitochondrial DNA haplogroups influence AIDS progression". AIDS 22 (18): 2429–39. November 2008. doi:10.1097/QAD.0b013e32831940bb. PMID 19005266.
- ↑ "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation 30 (2): E386–94. February 2009. doi:10.1002/humu.20921. PMID 18853457.
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Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups | |||||||||||||||||||||||||||||||||||||||
| Mitochondrial Eve (L) | |||||||||||||||||||||||||||||||||||||||
| L0 | L1–6 | ||||||||||||||||||||||||||||||||||||||
| L1 | L2 | L3 | L4 | L5 | L6 | ||||||||||||||||||||||||||||||||||
| M | N | ||||||||||||||||||||||||||||||||||||||
| CZ | D | E | G | Q | O | A | S | R | I | W | X | Y | |||||||||||||||||||||||||||
| C | Z | B | F | R0 | pre-JT | P | U | ||||||||||||||||||||||||||||||||
| HV | JT | K | |||||||||||||||||||||||||||||||||||||
| H | V | J | T | ||||||||||||||||||||||||||||||||||||
 |  |
