Biology:Haplogroup P (mtDNA)

From HandWiki
Short description: Human mitochondrial DNA haplogroup
Haplogroup P
Dispersión del haplogrupo P (ADNmt).PNG
Possible time of origin50,000 years[1]
Possible place of originSoutheast Asia
AncestorR
Descendants16176, P3, P4, P5, P6, P7, P9
Defining mutations15607[2]

In human mitochondrial genetics, Haplogroup P is a human mitochondrial DNA (mtDNA) haplogroup.

Origin

Haplogroup P is a descendant of Haplogroup R.

Distribution

Today, P is most commonly found in Oceania, especially in Papuans, Melanesians, indigenous Australians,[3] It's 1.4% in mainstream Filipinos but 1.13% in Luzon, 1.78% in Visayas, 1.43% in Mindanao.[4] It is much higher in Sub-Filipinos groups, 6.67% in Bugkalot and 11.2% in Maranao.[5] It was found in the Philippines Negrito Aeta of Bataan at 40%.[6] It is also found in the Malaysians at 0.9%, including Indonesians.

Subclades

Tree

This phylogenetic tree of haplogroup P subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[2] and subsequent published research.

  • P
    • (16176)
      • P1
        • P1d
          • P1d1
      • P2'10
        • P2
        • P10
      • P8
    • P3
      • P3a
      • P3b
        • P3b1
    • P4
      • P4a
        • P4a1
      • P4b
        • P4b1
    • P5
    • P6
    • P7
    • P9

See also

Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)    
L0 L1–6  
L1 L2   L3     L4 L5 L6
M N  
CZ D E G Q   O A S R   I W X Y
C Z B F R0   pre-JT   P   U
HV JT K
H V J T

References

  1. Hudjashov, Georgi et al. 2007. Revealing the prehistoric settlement of Australia by Y chromosome and mtDNA analysis. PNAS May 22, 2007 vol. 104 no. 21 8726-8730
  2. 2.0 2.1 van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation 30 (2): E386–E394. doi:10.1002/humu.20921. PMID 18853457. 
  3. Friedlaender et al. 2005 April, Expanding Southwest Pacific Mitochondrial Haplogroups P and Q , 22 (6): 1506
  4. Philippine Mitochondrial DNA Diversity: A Populated Viaduct between Taiwan and Indonesia? ,by Kristina A. Tabbada ,https://www.researchgate.net/publication/26813491_Philippine_Mitochondrial_DNA_Diversity_A_Populated_Viaduct_between_Taiwan_and_Indonesia
  5. Complete mtDNA genomes of Filipino ethnolinguistic groups: A melting pot of recent and ancient lineages in the Asia-Pacific region, by Catherine Hill, A Mitochondrial Stratigraphy for Island Southeast Asia
  6. Delfin F. et al 2013. Complete mtDNA genomes of Filipino ethnolinguistic groups: a melting pot of recent and ancient lineages in the Asia-Pacific region. Eur J Hum Genet. 2013 Jun 12. doi: 10.1038/ejhg.2013.122.

External links