Biology:Limulus clotting factor B
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Limulus clotting factor B | |||||||||
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Identifiers | |||||||||
EC number | 3.4.21.85 | ||||||||
CAS number | 848851-53-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Limulus clotting factor B (EC 3.4.21.85) is an enzyme.[1] This enzyme catalyses the following chemical reaction
- Selective cleavage of -Arg98-Ile- bond in limulus proclotting enzyme to form active clotting enzyme
From the hemocyte granules of the horseshoe crabs Limulus and Tachypleus. This enzyme is downstream of Limulus clotting factor C, but upstream of Limulus clotting enzyme.[2]
References
- ↑ "Purification and properties of intracellular clotting factor, factor B, from horseshoe crab (Tachypleus tridentatus) hemocytes". Journal of Biochemistry 99 (3): 847–57. March 1986. doi:10.1093/oxfordjournals.jbchem.a135545. PMID 3519594.
- ↑ Iwanaga, S (May 2007). "Biochemical principle of Limulus test for detecting bacterial endotoxins.". Proceedings of the Japan Academy. Series B, Physical and Biological Sciences 83 (4): 110–9. doi:10.2183/pjab.83.110. PMID 24019589. Bibcode: 2007PJAB...83..110I.
External links
- Limulus+clotting+factor+_overbar_B_ at the US National Library of Medicine Medical Subject Headings (MeSH)
Original source: https://en.wikipedia.org/wiki/Limulus clotting factor B.
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