Biology:Prosthecobacter

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Prosthecobacter is a genus of bacteria from the phylum Verrucomicrobiota with a distinctive characteristic; the presence of tubulin-like genes. Tubulins, which are components of the microtubule, have never been observed in Gracilicutes before.

Tubulin was long thought to be specific to eukaryotes. More recently, however, several prokaryotic proteins have been shown to be related to tubulin.[1][2][3][4]

Most bacteria have a homologous structure, FtsZ. Prosthecobacter are the exception to this, containing genes that have higher sequence homology to eukaryotic tubulin than FtsZ.

These genes are called bacterial tubulin a (BtubA) and bacterial tubulin b (BtubB). The properties are not exactly same. However, surface loops and microtubules are extremely similar.

Phylogeny

The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN)[5] and National Center for Biotechnology Information (NCBI).[6]

16S rRNA based LTP_10_2024[7][8][9] 120 marker proteins based GTDB 10-RS226[10][11][12]
Prosthecobacter

P. fluviatilis Takeda et al. 2008

P. vanneervenii Hedlund et al. 1998

Brevifollis gellanilyticus Otsuka et al. 2013

P. debontii Hedlund et al. 1998

P. dejongeii Hedlund et al. 1998

P. algae Lee et al. 2014

P. fusiformis Staley et al. 1976 ex Staley et al. 1980

Prosthecobacter

P. vanneervenii

Brevifollis gellanilyticus

P. debontii

P. fusiformis

P. algae

P. dejongeii

See also

References

  1. "Tubulin and FtsZ form a distinct family of GTPases". Nature Structural Biology 5 (6): 451–8. June 1998. doi:10.1038/nsb0698-451. PMID 9628483. 
  2. "Genes for the cytoskeletal protein tubulin in the bacterial genus Prosthecobacter". Proceedings of the National Academy of Sciences of the United States of America 99 (26): 17049–54. December 2002. doi:10.1073/pnas.012516899. PMID 12486237. Bibcode2002PNAS...9917049J. 
  3. "Archaeal origin of tubulin". Biology Direct 7: 10. March 2012. doi:10.1186/1745-6150-7-10. PMID 22458654. 
  4. "Treadmilling of a prokaryotic tubulin-like protein, TubZ, required for plasmid stability in Bacillus thuringiensis". Genes & Development 21 (11): 1340–52. June 2007. doi:10.1101/gad.1546107. PMID 17510284. 
  5. Template:Lpsn3
  6. Schoch CL. "Prosthecobacter". National Center for Biotechnology Information (NCBI) taxonomy database. https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?command=show&mode=tree&id=48463&lvl=3. Retrieved 2025-06-05. 
  7. "The LTP". https://imedea.uib-csic.es/mmg/ltp/#LTP. 
  8. "LTP_all tree in newick format". https://imedea.uib-csic.es/mmg/ltp/wp-content/uploads/ltp/LTP_all_10_2024.ntree. 
  9. "LTP_10_2024 Release Notes". https://imedea.uib-csic.es/mmg/ltp/wp-content/uploads/ltp/LTP_10_2024_release_notes.pdf. 
  10. "GTDB release 10-RS226". https://gtdb.ecogenomic.org/about#4%7C. 
  11. "bac120_r226.sp_label". https://data.gtdb.ecogenomic.org/releases/release226/226.0/auxillary_files/bac120_r226.sp_labels.tree. 
  12. "Taxon History". https://gtdb.ecogenomic.org/taxon_history/. 

Wikidata ☰ Q21228407 entry