Biology:Pterin deaminase
From HandWiki
pterin deaminase | |||||||||
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Identifiers | |||||||||
EC number | 3.5.4.11 | ||||||||
CAS number | 9025-04-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a pterin deaminase (EC 3.5.4.11) is an enzyme that catalyzes the chemical reaction
- 2-amino-4-hydroxypteridine + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 2,4-dihydroxypteridine + NH3
Thus, the two substrates of this enzyme are 2-amino-4-hydroxypteridine and H2O, whereas its two products are 2,4-dihydroxypteridine and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is 2-amino-4-hydroxypteridine aminohydrolase. This enzyme is also called acrasinase.
References
- "A bacterial pterin deaminase". J. Biol. Chem. 234 (4): 955–61. 1959. PMID 13654299.
- "Catabolism of pteridine cofactors. II. A specific pterin deaminase in rat liver". Biochim. Biophys. Acta 184 (3): 589–96. 1969. doi:10.1016/0304-4165(69)90273-6. PMID 5821022.
![]() | Original source: https://en.wikipedia.org/wiki/Pterin deaminase.
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