Biology:S-adenosylhomocysteine deaminase
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S-adenosylhomocysteine deaminase | |||||||||
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Identifiers | |||||||||
EC number | 3.5.4.28 | ||||||||
CAS number | 125149-24-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a S-adenosylhomocysteine deaminase (EC 3.5.4.28) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-homocysteine + H2O [math]\displaystyle{ \rightleftharpoons }[/math] S-inosyl-L-homocysteine + NH3
Thus, the two substrates of this enzyme are S-adenosyl-L-homocysteine and H2O, whereas its two products are S-inosyl-L-homocysteine and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is S-adenosyl-L-homocysteine aminohydrolase. This enzyme is also called adenosylhomocysteine deaminase.
References
- "Purification and characterization of S-adenosylhomocysteine deaminase from streptonigrin-producing Streptomyces flocculus". J. Bacteriol. 171 (12): 6840–4. 1989. PMID 2592350.
![]() | Original source: https://en.wikipedia.org/wiki/S-adenosylhomocysteine deaminase.
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