Biology:Serralysin
From HandWiki
| Serralysin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.24.40 | ||||||||
| CAS number | 70851-98-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Serralysin (EC 3.4.24.40, Pseudomonas aeruginosa alkaline proteinase, Escherichia freundii proteinase, Serratia marcescens extracellular proteinase, Serratia marcescens metalloproteinase, Pseudomonas aeruginosa alk. protease, Serratia marcescens metalloprotease) is an enzyme.[1][2][3][4][5][6][7][8] This enzyme catalyses the following chemical reaction
- Preferential cleavage of bonds with hydrophobic residues in P1'
This extracellular endopeptidase is present in Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.
References
- ↑ "Comparison of the specificities of various neutral proteinases from microorganisms". Archives of Biochemistry and Biophysics 123 (3): 572–88. March 1968. doi:10.1016/0003-9861(68)90179-3. PMID 4967801.
- ↑ "On the specificity of Pseudomonas aeruginosa alkaline proteinase with synthetic peptides". Biochimica et Biophysica Acta (BBA) - Enzymology 309 (2): 414–29. June 1973. doi:10.1016/0005-2744(73)90040-5. PMID 4199986.
- ↑ "Purification and properties of an extracellular proteinase of psychrophilic Escherichia freundii". European Journal of Biochemistry 44 (1): 87–96. May 1974. doi:10.1111/j.1432-1033.1974.tb03460.x. PMID 4212288.
- ↑ "Purification and characterization of the extracellular proteinase of Serratia marcescens". Biochimica et Biophysica Acta (BBA) - Enzymology 569 (2): 293–301. August 1979. doi:10.1016/0005-2744(79)90065-2. PMID 383155.
- ↑ "Purification and characterization of two Serratia marcescens proteases". Zentralblatt für Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology 257 (1): 6–19. May 1984. PMID 6380155.
- ↑ "Cloning and sequencing of Serratia protease gene". Nucleic Acids Research 14 (14): 5843–55. July 1986. doi:10.1093/nar/14.14.5843. PMID 3016665.
- ↑ "Cloning of genes encoding extracellular metalloproteases from Erwinia chrysanthemi EC16". Journal of Bacteriology 172 (10): 5803–15. October 1990. doi:10.1128/jb.172.10.5803-5815.1990. PMID 2211513.
- ↑ "Complete nucleotide sequence of the structural gene for alkaline proteinase from Pseudomonas aeruginosa IFO 3455". Infection and Immunity 58 (12): 4083–8. December 1990. doi:10.1128/IAI.58.12.4083-4088.1990. PMID 2123832.
External links
- Serralysin at the US National Library of Medicine Medical Subject Headings (MeSH)
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