Biology:UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase
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Short description: Class of enzymes
| UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.285 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase (EC 2.4.1.285, neoK (gene)) is an enzyme with systematic name UDP-N-acetyl-alpha-D-glucosamine:ribostamycin N-acetylglucosaminyltransferase.[1] This enzyme catalyses the following chemical reaction
- UDP-N-acetyl-alpha-D-glucosamine + ribostamycin [math]\displaystyle{ \rightleftharpoons }[/math] UDP + 2'''-acetyl-6'''-hydroxyneomycin C
Involved in biosynthesis of the aminoglycoside antibiotic neomycin.
References
- ↑ "Involvement of two distinct N-acetylglucosaminyltransferases and a dual-function deacetylase in neomycin biosynthesis". ChemBioChem 9 (6): 865–9. April 2008. doi:10.1002/cbic.200700717. PMID 18311744.
External links
- UDP-GlcNAc:ribostamycin+N-acetylglucosaminyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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