Chemistry:Benzylthiouracil
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Short description: Chemical compound
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| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Oral |
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| Excretion | Renal |
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| Formula | C11H10N2OS |
| Molar mass | 218.27 g·mol−1 |
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Benzylthiouracil (BTU) is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.
Adverse effects
Benzylthiouracil has been associated with severe adverse effects, notably vasculitis and subsequent ANCA-positive glomerulonephritis, as well as isolated reports of lung damage.[1][2][3][4]
References
- ↑ "[ANCA associated glomerulonephritis related to benzylthiouracil]" (in French). Rev Méd Interne 23 (10): 853–6. 2002. doi:10.1016/S0248-8663(02)00694-X. PMID 12428489.
- ↑ "[Vasculitis with renal and pulmonary involvement in a patient receiving benzylthiouracil for Graves disease]" (in French). Rev Méd Interne 23 (10): 857–61. 2002. doi:10.1016/S0248-8663(02)00704-X. PMID 12428490.
- ↑ "[Benzylthiouracil induced ANCA-positive vasculitis]" (in French). Presse Médicale 33 (19 Pt 1): 1331–3. 2004. doi:10.1016/S0755-4982(04)98919-1. PMID 15615240.
- ↑ "ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil". Eur J Pediatr 165 (7): 435–6. 2006. doi:10.1007/s00431-005-0053-4. PMID 16622664.
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