Chemistry:Butanilicaine

Butanilicaine

Names
IUPAC name N2-Butyl-N1-(2-chloro-6-methylphenyl)glycinamide
Systematic IUPAC name 2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide
Identifiers
CAS Number	3785-21-5 N
3D model (JSmol)	Interactive image
ChEBI	CHEBI:55518 Y
ChEMBL	ChEMBL2104238 N
ChemSpider	21004 Y
PubChem CID	22379
UNII	7X3WV51F4N Y
InChI InChI=1S/C13H19ClN2O/c1-3-4-8-15-9-12(17)16-13-10(2)6-5-7-11(13)14/h5-7,15H,3-4,8-9H2,1-2H3,(H,16,17) Y Key: VWYQKFLLGRBICZ-UHFFFAOYSA-N Y InChI=1/C13H19ClN2O/c1-3-4-8-15-9-12(17)16-13-10(2)6-5-7-11(13)14/h5-7,15H,3-4,8-9H2,1-2H3,(H,16,17) Key: VWYQKFLLGRBICZ-UHFFFAOYAQ
SMILES CCCCNCC(=O)NC1=C(C=CC=C1Cl)C
Properties
Chemical formula	C13H19ClN2O
Molar mass	254.75576
Pharmacology
1=ATC code }}	N01BB05 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Butanilicaine is a local anesthetic. It is also known by the name Hostacaine.

Synthesis

Thieme Synthesis: Patents:

The amide formation between 2-Chloro-6-Methylaniline [87-63-8] (1) and Chloroacetyl chloride (2) gives 2-Chloro-n-(2-chloro-6-methylphenyl)acetamide [6307-67-1] (3). Alkylation with N-Butylamine (4) completed the synthesis of Butanilicaine (5).