Chemistry:3-(p-Fluorobenzoyloxy)tropane
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| Routes of administration | insufflated |
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| Formula | C15H18FNO2 |
| Molar mass | 263.312 g·mol−1 |
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3β-(p-Fluorobenzoyloxy)tropane, (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 4-fluorobenzoic acid ester, 4-fluorotropacocaine, 3-Pseudotropyl-4-fluorobenzoate, 3-pseudotropyl-4-fluorobenzoate, pFBT) is a tropane derivative drug which acts as a local anaesthetic, having around 30% the stimulant potency of cocaine but around the same potency as a local anaesthetic.[citation needed] It has been investigated as a potential radiolabelled agent for studying receptor binding,[1] but was not adopted for this application. The main application for fluorotropacocaine, however, has been as a designer drug analogue of cocaine, first detected by the EMCDDA in 2008,[2][3] and subsequently sold as an ingredient of various "bath salt" powder products, usually mixed in combination with other stimulant drugs such as caffeine, dimethocaine, desoxypipradrol or substituted cathinone derivatives.[4]
See also
References
- ↑ Ali M. Emran. New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. Springer, 1991. p84. ISBN:0-306-44035-0
- ↑ "Bioanalysis of new designer drugs". Bioanalysis 2 (5): 965–79. May 2010. doi:10.4155/bio.10.32. PMID 21083227.
- ↑ "The syntheses and characterization 3β-(4-fluorobenzoyloxy)tropane (fluorotropacocaine) and its 3α isomer". Drug Testing and Analysis 4 (1): 33–8. January 2012. doi:10.1002/dta.362. PMID 22102564.
- ↑ "Identification of ten new designer drugs by GC-MS, UPLC-QTOF-MS, and NMR as part of a police investigation of a Danish internet company". Drug Testing and Analysis 4 (5): 342–54. May 2012. doi:10.1002/dta.358. PMID 22102551.
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