Chemistry:Ethanolamine-O-sulfate
From HandWiki
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| Names | |
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| Preferred IUPAC name
2-Aminoethyl hydrogen sulfate | |
| Other names
Aminoethyl sulfate; 2-Aminoethyl hydrogen sulphate; Sulfuric acid mono 2-aminoethyl ester; WAS-34
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| Identifiers | |
3D model (JSmol)
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| Abbreviations | EOS |
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PubChem CID
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| Properties | |
| C2H7NO4S | |
| Molar mass | 141.14 g·mol−1 |
| Melting point | 277 °C (531 °F; 550 K) (decomposes) |
| Hazards | |
| GHS pictograms | 
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| GHS Signal word | Warning |
| H302, H315, H319, H335 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
Tracking categories (test):
Ethanolamine-O-sulfate (EOS) is an ester of sulfuric acid and ethanolamine. EOS is a GABA transaminase inhibitor which prevents the metabolism of GABA.[2] It is used as a biochemical tool in studies involving GABA.
EOS is also a diuretic[3] and an anticonvulsant.[4]
References
- ↑ 2-Aminoethyl hydrogen sulfate at Sigma-Aldrich
- ↑ "Ethanolamine-O-sulfate enhances gamma-aminobutyric acid secretion into hypophysial portal blood and lowers serum prolactin concentrations". Neuroendocrinology 37 (5): 397–9. 1983. doi:10.1159/000123580. PMID 6646351.
- ↑ German Patent DE2345291: Diuretic aminoalkyl sulfates; Somani, Pitambar; Martin, Donald Lyons (1974)
- ↑ Anlezark, Gill; Horton, Roger W.; Meldrum, Brian S.; Sawaya, M. Christina B. (1976). "Anticonvulsant action of ethanolamine-O-sulfate and di-n-propylacetate and the metabolism of γ-aminobutyric acid (GABA) in mice with audiogenic seizures". Biochemical Pharmacology 25 (4): 413–417. doi:10.1016/0006-2952(76)90343-9. PMID 779794.
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