Chemistry:Euphol
From HandWiki
Euphol is a tetracyclic triterpene with the molecular formula C
30H
50O.[1]
Natural occurrence
Euphol was isolated from cucumber and is an active principle of various plant species belonging to the Euphorbia genus.[2]
Uses
The compound is known for its potential hypotensive, anti-inflammatory, and antitumor activities.[3][4][5]
References
- ↑ Shaban, Aya Fadle; Abd El Kawy, Mostafa A.; Hamed, Ahmed Ragab; Salama, Abeer; El Motayam, Amira Kamal (1 June 2025). "Euphol: chemical and biological aspects: A review". Egyptian Journal of Chemistry 68 (6): 705–726. doi:10.21608/ejchem.2024.322067.10466. ISSN 0449-2285. https://ejchem.journals.ekb.eg/article_386772.html. Retrieved 22 July 2025.
- ↑ Silva, Viviane A. O.; Rosa, Marcela N.; Miranda-Gonçalves, Vera; Costa, Angela M.; Tansini, Aline; Evangelista, Adriane F.; Martinho, Olga; Carloni, Adriana C. et al. (April 2019). "Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells". Investigational New Drugs 37 (2): 223–237. doi:10.1007/s10637-018-0620-y. ISSN 1573-0646. PMID 29931585.
- ↑ Zhao, Maoyuan; Yang, Yi; Nian, Qing; Shen, Caifei; Xiao, Xiaolin; Liao, Wenhao; Zheng, Qiao; Zhang, Gang et al. (1 February 2023). "Phytochemicals and mitochondria: Therapeutic allies against gastric cancer". Phytomedicine 110. doi:10.1016/j.phymed.2022.154608. ISSN 0944-7113. PMID 36586205. https://www.sciencedirect.com/science/article/abs/pii/S0944711322006961. Retrieved 22 July 2025.
- ↑ Singh, G. B.; Singh, Surjeet; Sharma, M. L.; Suri, O. P.; Chopra, C. L.; Ammon, H. P. T. (December 1989). "Hypotensive Activity of 8,24-Euphadien-3β-ol (Euphol)" (in en). Planta Medica 55 (6): 498–500. doi:10.1055/s-2006-962079. ISSN 0032-0943. PMID 2616667. Bibcode: 1989PlMed..55..498S. https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-2006-962079. Retrieved 22 July 2025.
- ↑ Cruz, L. S.; De Oliveira, T. L.; Kanunfre, C. C.; Paludo, K. S.; Minozzo, B. R.; Prestes, A. P.; Wang, M.; Fernandes, D. et al. (2018). "Pharmacokinetics and cytotoxic study of euphol from Euphorbia umbellata (Bruyns) Pax latex". Phytomedicine 47: 105–112. doi:10.1016/j.phymed.2018.04.055. PMID 30166094.
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