Chemistry:Monalazone
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Short description: Chemical compound
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| Trade names | Naclobenz-Natrium, Spergisin, Speton |
| Other names | p-(Chlorosulfamoyl)benzoic acid |
| Routes of administration | Vaginal |
| Drug class | Disinfectant |
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| Formula | C7H6ClNO4S |
| Molar mass | 235.64 g·mol−1 |
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Monalazone, used as monalazone disodium (INN; the disodium salt) and sold under the brand names Naclobenz-Natrium, Spergisin, and Speton, is a vaginal disinfectant or antiseptic and spermicidal contraceptive.[1][2][3][4] It is a sulfonylbenzoic acid derivative and is closely related structurally to halazone.[2] The compound was synthesized in 1937.[1] A vaginal tablet combination of 0.125 mg estradiol benzoate and 10 mg monalazone was previously marketed under the brand name Malun 25.[5][3]
References
- ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 834–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA834.
- ↑ 2.0 2.1 Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 31 October 1999. pp. 185–. ISBN 978-0-7514-0499-9. https://books.google.com/books?id=mqaOMOtk61IC&pg=PA185.
- ↑ 3.0 3.1 The Extra Pharmacopoeia. Pharmaceutical Press. 1993. p. 800. ISBN 978-0-85369-300-0. https://books.google.com/books?id=EGZWAAAAYAAJ. "Monalazone disodium is an antiseptic closely related structurally to halazone (see p.796) and is used as a vaginal disinfectant and spermicide. Proprietary Names Malun N. Sperlisin. Multi-ingredient preparations. Malun."
- ↑ RÖMPP Lexikon Chemie. 10. Auflage, 1996-1999. Thieme. 16 July 2014. pp. 2000–2001. ISBN 978-3-13-200031-5. https://books.google.com/books?id=TD3OAwAAQBAJ&pg=PA2000.
- ↑ Klinische Endokrinologie für Frauenärzte. Springer-Verlag. 17 April 2013. pp. 527–. ISBN 978-3-662-08110-5. https://books.google.com/books?id=YTiuBgAAQBAJ&pg=PA527.
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