Medicine:Combined pulmonary fibrosis and emphysema
From HandWiki
| Combined pulmonary fibrosis and emphysema | |
|---|---|
| Other names | CPFE |
| Specialty | Pulmonology |
Combined pulmonary fibrosis and emphysema (CPFE), describes a medical syndrome involving both pulmonary fibrosis and emphysema.[1][2] The combination is most commonly found in male smokers. Pulmonary function tests typically show preserved lung volume with very low transfer factor.[3]
Presentation
CFPE is characterised by shortness of breath, and reduced oxygen concentration (reflecting gas exchange abnormalities). Imaging shows upper-lobe emphysema, and lower-lobe interstitial fibrosis.[4] CFPE is often complicated by pulmonary hypertension, acute lung injury, lung cancer, and coronary artery disease.[4]
Diagnosis
The diagnosis is confirmed with high resolution CT scan.[5]
References
- ↑ Cottin, V; Cordier JF (June 2005). "Combined pulmonary fibrosis and emphysema: an experimental and clinically relevant phenotype". American Journal of Respiratory and Critical Care Medicine 172 (12): 1605; author reply 1605–6. doi:10.1164/ajrccm.172.12.1605a. PMID 16339012. http://ajrccm.atsjournals.org/cgi/content/full/172/12/1605a. Retrieved 2009-02-23.
- ↑ Cottin, V et al. (February 2006). "Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity". European Respiratory Journal 26 (4): 586–593. doi:10.1183/09031936.05.00021005. PMID 16204587.
- ↑ Papiris, SA; Triantafillidou, C; Manali, ED (February 2013). "Combined pulmonary fibrosis and emphysema". Expert Review of Respiratory Medicine 7 (1): 19–31. doi:10.1586/ers.12.80. PMID 23362797.
- ↑ 4.0 4.1 Wand, O; Kramer, MR (January 2018). "The Syndrome of Combined Pulmonary Fibrosis and Emphysema - CPFE". Harefuah 157 (1): 28–33. PMID 29374870.
- ↑ Jankowich, MD; Rounds, SI (January 2012). "Combined pulmonary fibrosis and emphysema syndrome: a review". Chest 141 (1): 222–231. doi:10.1378/chest.11-1062. PMID 22215830.
External links
| Classification | |
|---|---|
| External resources |
 |  |
