Biology:Pyrimidine-5'-nucleotide nucleosidase
From HandWiki
| pyrimidine-5'-nucleotide nucleosidase | |||||||||
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| Identifiers | |||||||||
| EC number | 3.2.2.10 | ||||||||
| CAS number | 9023-31-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a pyrimidine-5'-nucleotide nucleosidase (EC 3.2.2.10) is an enzyme that catalyzes the chemical reaction
- a pyrimidine 5'-nucleotide + H2O [math]\displaystyle{ \rightleftharpoons }[/math] D-ribose 5-phosphate + a pyrimidine base
Thus, the two substrates of this enzyme are pyrimidine 5'-nucleotide and H2O, whereas its two products are D-ribose 5-phosphate and pyrimidine base.
This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase. Other names in common use include pyrimidine nucleotide N-ribosidase, and Pyr5N. This enzyme participates in pyrimidine metabolism.
References
- Imada A (1967). "Degradation of pyrimidine nucleotides by enzyme systems of Streptomyces. II. Pyrimidine 5'-nucleotide phosphoribo(deoxyribo) hydrolase of Streptomyces virginiae". J. Gen. Appl. Microbiol. 13 (3): 267–278. doi:10.2323/jgam.13.267.
- "Degradation of pyrimidine nucleotides by enzyme systems of Streptomyces. I. Ribose-5-phosphate formation from pyrimidine nucleotides". J. Gen. Appl. Microbiol. 13 (3): 255–265. 1967. doi:10.2323/jgam.13.255.
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