Biology:Rhamnogalacturonan hydrolase
From HandWiki
| Rhamnogalacturonan hydrolase | |||||||||
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| Identifiers | |||||||||
| EC number | 3.2.1.171 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Rhamnogalacturonan hydrolase (EC 3.2.1.171, rhamnogalacturonase A, RGase A, RG-hydrolase) is an enzyme with systematic name rhamnogalacturonan alpha-D-GalA-(1->2)-alpha-L-Rha hydrolase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- Endohydrolysis of alpha-D-GalA-(1->2)-alpha-L-Rha glycosidic bond in the rhamnogalacturonan I backbone with initial inversion of anomeric configuration releasing oligosaccharides with beta-D-GalA at the reducing end.
The enzyme is part of the degradation system for rhamnogalacturonan I in Aspergillus aculeatus.
References
- ↑ "The crystal structure of rhamnogalacturonase A from Aspergillus aculeatus: a right-handed parallel beta helix". Structure 5 (4): 533–44. April 1997. doi:10.1016/s0969-2126(97)00209-8. PMID 9115442.
- ↑ "Cloning and characterization of two structurally and functionally divergent rhamnogalacturonases from Aspergillus aculeatus". The Journal of Biological Chemistry 269 (46): 29182–9. November 1994. PMID 7961884.
- ↑ "The backbone of the pectic polysaccharide rhamnogalacturonan I is cleaved by an endohydrolase and an endolyase". Glycobiology 5 (8): 783–9. December 1995. doi:10.1093/glycob/5.8.783. PMID 8720076.
- ↑ "Crystallization and preliminary X-ray studies of rhamnogalacturonase A from Aspergillus aculeatus". Acta Crystallographica Section D 53 (Pt 1): 105–7. January 1997. doi:10.1107/s0907444996010785. PMID 15299976.
- ↑ "Stereochemical course of hydrolysis catalysed by alpha-L-rhamnosyl and alpha-D-galacturonosyl hydrolases from Aspergillus aculeatus". Biochemical and Biophysical Research Communications 242 (3): 552–9. January 1998. doi:10.1006/bbrc.1997.8009. PMID 9464254.
External links
- Rhamnogalacturonan+hydrolase at the US National Library of Medicine Medical Subject Headings (MeSH)
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