Biology:UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing)
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Short description: Class of enzymes
| UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.2.1.184 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing) (EC 3.2.1.184, UDP-Bac2Ac4Ac 2-epimerase, NeuC) is an enzyme with systematic name UDP-N,N'-diacetylbacillosamine hydrolase (2-epimerising).[1][2] This enzyme catalyses the following chemical reaction
- UDP-N,N'-diacetylbacillosamine + H2O [math]\displaystyle{ \rightleftharpoons }[/math] UDP + 2,4-diacetamido-2,4,6-trideoxy-D-mannopyranose
This enzyme requires Mg2+. It is involved in biosynthesis of legionaminic acid.
References
- ↑ "Biosynthesis of CMP-N,N'-diacetyllegionaminic acid from UDP-N,N'-diacetylbacillosamine in Legionella pneumophila". Biochemistry 47 (10): 3272–82. March 2008. doi:10.1021/bi702364s. PMID 18275154.
- ↑ "The CMP-legionaminic acid pathway in Campylobacter: biosynthesis involving novel GDP-linked precursors". Glycobiology 19 (7): 715–25. July 2009. doi:10.1093/glycob/cwp039. PMID 19282391.
External links
- UDP-N,N'-diacetylbacillosamine+2-epimerase+(hydrolysing) at the US National Library of Medicine Medical Subject Headings (MeSH)
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