Biology:Glycoside hydrolase family 101

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Short description: Family of glycoside hydrolases
Endo-alpha-N-acetylgalactosaminidase
Identifiers
SymbolGlyco_hydro_101
PfamPF12905
Pfam clanCL0058
CAZyGH101
CDDcd14244
Glycoside hydrolases related to GH101 family
Identifiers
SymbolGHL
PfamPF11308
Pfam clanCL0058

In molecular biology, glycoside hydrolase family 101 is a family of glycoside hydrolases.

Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]

Glycoside hydrolase family GH101 includes enzymes with endo-α-N-acetylgalactosaminidase EC 3.2.1.97 activity and can be split into several subfamilies.[8]

External links

References

  1. "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 7090–7094. 1995. doi:10.1073/pnas.92.15.7090. PMID 7624375. Bibcode1995PNAS...92.7090H. 
  2. "Structures and mechanisms of glycosyl hydrolases". Structure 3 (9): 853–859. 1995. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779. 
  3. "Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999.". http://www.expasy.ch/cgi-bin/lists?glycosid.txt. 
  4. "Home" (in en). http://www.cazy.org/. 
  5. Lombard, Vincent; Golaconda Ramulu, Hemalatha; Drula, Elodie; Coutinho, Pedro M.; Henrissat, Bernard (2014-01-01). "The carbohydrate-active enzymes database (CAZy) in 2013" (in en). Nucleic Acids Research 42 (D1): D490–D495. doi:10.1093/nar/gkt1178. ISSN 0305-1048. PMID 24270786. 
  6. "Glycoside Hydrolase Family 101" (in en). http://www.cazypedia.org/index.php/Glycoside_Hydrolase_Family_101. 
  7. CAZypedia Consortium (2018-12-01). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology 28 (1): 3–8. doi:10.1093/glycob/cwx089. ISSN 1460-2423. PMID 29040563. https://hal.archives-ouvertes.fr/hal-01886461/file/Hehemann_2018_01.pdf. 
  8. Naumoff DG (2010). "GH101 family of glycoside hydrolases: subfamily structure and evolutionary connections with other families.". J Bioinform Comput Biol 8 (3): 437–451. doi:10.1142/s0219720010004628. PMID 20556855.