Biology:RRNA N-glycosylase
From HandWiki
| rRNA N-glycosylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Ricin A chain, Ricinus communis | |||||||||
| Identifiers | |||||||||
| EC number | 3.2.2.22 | ||||||||
| CAS number | 113756-12-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
rRNA N-glycosylase (EC 3.2.2.22, ribosomal ribonucleate N-glycosidase, nigrin b, RNA N-glycosidase, rRNA N-glycosidase, ricin, momorcochin-S, Mirabilis antiviral protein, gelonin, saporins) is an enzyme with systematic name rRNA N-glycohydrolase.[1] This enzyme catalyses the following chemical reaction
- Hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from eukaryotic ribosomes.
Ricin A-chain and related toxins show this activity. The only protein family known to have this activity is the ribosome-inactivating protein (RIP) family.
References
External links
- RRNA+N-glycosylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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