Biology:3-Deoxy-2-octulosonidase

From HandWiki
Short description: Class of enzymes
3-Deoxy-2-octulosonidase
Identifiers
EC number3.2.1.124
CAS number103171-48-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

3-Deoxy-2-octulosonidase (EC 3.2.1.124, 2-keto-3-deoxyoctonate hydrolase, octulosylono hydrolase, octulofuranosylono hydrolase, octulopyranosylonohydrolase) is an enzyme with systematic name capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase.[1] This enzyme catalyses the following chemical reaction

Endohydrolysis of the β-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides

The bacteriophage enzyme depolymerizes polysaccharides containing 3-deoxy-2-octulosonide in the cell wall of Escherichia coli.

References

  1. "A bacteriophage-associated glycanase cleaving beta-pyranosidic linkages of 3-deoxy-D-manno-2-octulosonic acid (KDO)". Biochemical and Biophysical Research Communications 136 (1): 329–35. April 1986. doi:10.1016/0006-291x(86)90914-9. PMID 3707579. 

External links