Biology:6-phospho-beta-glucosidase
| 6-phospho-beta-glucosidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.2.1.86 | ||||||||
| CAS number | 37205-51-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 6-phospho-beta-glucosidase (EC 3.2.1.86) is an enzyme that catalyzes the chemical reaction
- 6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H2O [math]\displaystyle{ \rightleftharpoons }[/math] D-glucose + D-glucose 6-phosphate
Thus, the two substrates of this enzyme are 6-phospho-beta-D-glucosyl-(1,4)-D-glucose and H2O, whereas its two products are D-glucose and D-glucose 6-phosphate.
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 6-phospho-beta-D-glucosyl-(1,4)-D-glucose glucohydrolase. Other names in common use include phospho-beta-glucosidase A, phospho-beta-glucosidase, and phosphocellobiase. This enzyme participates in glycolysis / gluconeogenesis.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1S6Y.
References
- "Cellobiose metabolism in Aerobacter aerogenes. 3. Cleavage of cellobiose monophosphate by a phospho- -glucosidase". J. Biol. Chem. 247 (11): 3420–3. 1972. PMID 4624114.
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