Biology:Glycoside hydrolase family 57
| Glycosyl hydrolase family 57 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Glyco_hydro_57 | ||||||||
| Pfam | PF03065 | ||||||||
| Pfam clan | CL0158 | ||||||||
| SCOP2 | 1k1x / SCOPe / SUPFAM | ||||||||
| CAZy | GH57 | ||||||||
| |||||||||
In molecular biology, glycoside hydrolase family 57 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]
Glycoside hydrolase family 57 CAZY GH_57 comprises enzymes with several known activities; alpha-amylase (EC 3.2.1.1), 4-alpha-glucanotransferase (EC 2.4.1.25), α-galactosidase (EC 3.2.1.22); amylopullulanase (EC 3.2.1.41); branching enzyme (EC 2.4.1.18). It includes a thermostable alpha-amylase with a broad substrate specificity from the archaebacterium Pyrococcus furiosus.[8]
External links
References
- ↑ "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 7090–7094. 1995. doi:10.1073/pnas.92.15.7090. PMID 7624375. Bibcode: 1995PNAS...92.7090H.
- ↑ "Structures and mechanisms of glycosyl hydrolases". Structure 3 (9): 853–859. 1995. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
- ↑ "Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999.". http://www.expasy.ch/cgi-bin/lists?glycosid.txt.
- ↑ "Home" (in en). http://www.cazy.org/.
- ↑ Lombard, Vincent; Golaconda Ramulu, Hemalatha; Drula, Elodie; Coutinho, Pedro M.; Henrissat, Bernard (2014-01-01). "The carbohydrate-active enzymes database (CAZy) in 2013" (in en). Nucleic Acids Research 42 (D1): D490–D495. doi:10.1093/nar/gkt1178. ISSN 0305-1048. PMID 24270786.
- ↑ "Glycoside Hydrolase Family 57" (in en). http://www.cazypedia.org/index.php/Glycoside_Hydrolase_Family_57.
- ↑ CAZypedia Consortium (2018-12-01). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology 28 (1): 3–8. doi:10.1093/glycob/cwx089. ISSN 1460-2423. PMID 29040563. https://hal.archives-ouvertes.fr/hal-01886461/file/Hehemann_2018_01.pdf.
- ↑ "The purification and characterization of an extremely thermostable alpha-amylase from the hyperthermophilic archaebacterium Pyrococcus furiosus.". J Biol Chem 268 (32): 24394–401. 1993. doi:10.1016/S0021-9258(20)80538-9. PMID 8226989.
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