Biology:Glycoside hydrolase family 8
| Glycosyl hydrolases family 8 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Glyco_hydro_8 | ||||||||
| Pfam | PF01270 | ||||||||
| Pfam clan | CL0059 | ||||||||
| PROSITE | PDOC00640 | ||||||||
| SCOP2 | 1cem / SCOPe / SUPFAM | ||||||||
| CAZy | GH8 | ||||||||
| |||||||||
In molecular biology, glycoside hydrolase family 8 is a family of glycoside hydrolases EC 3.2.1., which are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy website,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate-active enzymes.[6][7]
Glycoside hydrolase family 8 CAZY GH_8 comprises enzymes with several known activities; endoglucanase (EC 3.2.1.4); lichenase (EC 3.2.1.73); chitosanase (EC 3.2.1.132). These enzymes were formerly known as cellulase family D.[8]
References
- ↑ "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America 92 (15): 7090–4. July 1995. doi:10.1073/pnas.92.15.7090. PMID 7624375. Bibcode: 1995PNAS...92.7090H.
- ↑ "Structures and mechanisms of glycosyl hydrolases". Structure 3 (9): 853–9. September 1995. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
- ↑ "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal 316 (Pt 2): 695–6. June 1996. doi:10.1042/bj3160695. PMID 8687420.
- ↑ "Home" (in en). http://www.cazy.org/.
- ↑ "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research 42 (Database issue): D490–5. January 2014. doi:10.1093/nar/gkt1178. PMID 24270786.
- ↑ "Glycoside Hydrolase Family 8" (in en). http://www.cazypedia.org/index.php/Glycoside_Hydrolase_Family_8.
- ↑ CAZypedia Consortium (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology 28 (1): 3–8. doi:10.1093/glycob/cwx089. PMID 29040563. http://eprints.whiterose.ac.uk/122863/1/CAZypedia_20171003_Figures.pdf.
- ↑ "Cellulase families revealed by hydrophobic cluster analysis". Gene 81 (1): 83–95. September 1989. doi:10.1016/0378-1119(89)90339-9. PMID 2806912.
 |  |
