Biology:Glycoside hydrolase family 88

From HandWiki
Glycosyl Hydrolase Family 88
Identifiers
SymbolGlyco_hydro_88
PfamPF07470
Pfam clanCL0059
SCOP21nc5 / SCOPe / SUPFAM
CAZyGH88

In molecular biology, glycoside hydrolase family 88 is a family of glycoside hydrolases.

Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]

Glycoside hydrolase family 88 CAZY GH_88 includes enzymes with d-4,5 unsaturated β-glucuronyl hydrolase activity.[8][9]

References

  1. "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America 92 (15): 7090–4. July 1995. doi:10.1073/pnas.92.15.7090. PMID 7624375. Bibcode1995PNAS...92.7090H. 
  2. "Structures and mechanisms of glycosyl hydrolases". Structure 3 (9): 853–9. September 1995. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779. 
  3. "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal 316 (Pt 2): 695–6. June 1996. doi:10.1042/bj3160695. PMID 8687420. 
  4. "Home" (in en). http://www.cazy.org/. 
  5. "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research 42 (Database issue): D490–5. January 2014. doi:10.1093/nar/gkt1178. PMID 24270786. 
  6. "Glycoside Hydrolase Family 88" (in en). http://www.cazypedia.org/index.php/Glycoside_Hydrolase_Family_88. 
  7. CAZypedia Consortium (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology 28 (1): 3–8. doi:10.1093/glycob/cwx089. PMID 29040563. 
  8. "Unsaturated glucuronyl hydrolase of Bacillus sp. GL1: novel enzyme prerequisite for metabolism of unsaturated oligosaccharides produced by polysaccharide lyases.". Arch Biochem Biophys 368 (2): 367–74. 1999. doi:10.1006/abbi.1999.1305. PMID 10441389. 
  9. Ostrowski, Matthew P.; La Rosa, Sabina Leanti; Kunath, Benoit J.; Robertson, Andrew; Pereira, Gabriel; Hagen, Live H.; Varghese, Neha J.; Qiu, Ling et al. (April 2022). "Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota". Nature Microbiology 7 (4): 556–569. doi:10.1038/s41564-022-01093-0. PMID 35365790.