Biology:Glycoside hydrolase family 9
| Glycosyl hydrolase family 9 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Glyco_hydro_9 | ||||||||
| Pfam | PF00759 | ||||||||
| Pfam clan | CL0059 | ||||||||
| PROSITE | PDOC00511 | ||||||||
| SCOP2 | 1clc / SCOPe / SUPFAM | ||||||||
| CAZy | GH9 | ||||||||
| Membranome | 1017 | ||||||||
| |||||||||
In molecular biology, glycoside hydrolase family 9 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy web site,[4][5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[6][7]
Glycoside hydrolase family 9 CAZY GH_9 comprises enzymes with several known activities including endoglucanase (EC 3.2.1.4) and cellobiohydrolase (EC 3.2.1.91). These enzymes were formerly known as cellulase family E. Cellulases (Endoglucanases) EC 3.2.1.4 catalyse the endohydrolysis of 1,4-beta-D-glucosidic linkages in cellulose. GH9 family members have also been found in green microalgae (Chlamydomonas, Gonium and Volvox) that show highest sequence identity to endogenous GH9 cellulases from invertebrate metazoans [8][9]
References
- ↑ "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America 92 (15): 7090–4. July 1995. doi:10.1073/pnas.92.15.7090. PMID 7624375. Bibcode: 1995PNAS...92.7090H.
- ↑ "Structures and mechanisms of glycosyl hydrolases". Structure 3 (9): 853–9. September 1995. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
- ↑ "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal 316 (Pt 2): 695–6. June 1996. doi:10.1042/bj3160695. PMID 8687420.
- ↑ "Home" (in en). http://www.cazy.org/.
- ↑ "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research 42 (Database issue): D490-5. January 2014. doi:10.1093/nar/gkt1178. PMID 24270786.
- ↑ "Glycoside Hydrolase Family 9" (in en). http://www.cazypedia.org/index.php/Glycoside_Hydrolase_Family_9.
- ↑ CAZypedia Consortium (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology 28 (1): 3–8. doi:10.1093/glycob/cwx089. PMID 29040563.
- ↑ Guerriero G. Sergeant K. Legay S. Hausman J.-F. Cauchie H.-M. Ahmad I. Siddiqui K.S . Int. J. Mol. Sci. 2018, 19, 1782
- ↑ "Prosite". https://prosite.expasy.org/PDOC00511.
 |  |
