Biology:Iota-carrageenase

From HandWiki
Iota-carrageenase
Identifiers
EC number3.2.1.157
CAS number50936-37-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Iota-carrageenase (EC 3.2.1.157) is an enzyme with systematic name iota-carrageenan 4-beta-D-glycanohydrolase (configuration-inverting).[1][2][3] This enzyme catalyses the following chemical reaction

Endohydrolysis of (1->4)-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans

The main products of hydrolysis are iota-neocarratetraose sulfate and iota-neocarrahexaose sulfate.

References

  1. "iota-Carrageenases constitute a novel family of glycoside hydrolases, unrelated to that of kappa-carrageenases". The Journal of Biological Chemistry 275 (45): 35499–505. November 2000. doi:10.1074/jbc.m003404200. PMID 10934194. 
  2. "The iota-carrageenase of Alteromonas fortis. A beta-helix fold-containing enzyme for the degradation of a highly polyanionic polysaccharide". The Journal of Biological Chemistry 276 (43): 40202–9. October 2001. doi:10.1074/jbc.M100670200. PMID 11493601. 
  3. "The structural bases of the processive degradation of iota-carrageenan, a main cell wall polysaccharide of red algae". Journal of Molecular Biology 334 (3): 421–33. November 2003. doi:10.1016/j.jmb.2003.09.056. PMID 14623184. 

External links