Biology:Mucinaminylserine mucinaminidase
From HandWiki
| mucinaminylserine mucinaminidase | |||||||||
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| Identifiers | |||||||||
| EC number | 3.2.1.110 | ||||||||
| CAS number | 59793-96-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a mucinaminylserine mucinaminidase (EC 3.2.1.110) is an enzyme that catalyzes the chemical reaction
- D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O [math]\displaystyle{ \rightleftharpoons }[/math] D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine
Thus, the two substrates of this enzyme are D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine and H2O, whereas its two products are D-galactosyl-3-N-acetyl-beta-D-galactosamine and L-serine.
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase. Other names in common use include endo-alpha-N-acetylgalactosaminidase, and endo-alpha-N-acetyl-D-galactosaminidase.
References
- "Characterization of an endo-alpha-N-acetyl galactosaminidase from Diplococcus pneumoniae". Biochem. Biophys. Res. Commun. 70 (3): 738–45. 1976. doi:10.1016/0006-291X(76)90654-9. PMID 7253.
- "Partial purification and characterization of an endo-alpha-N-acetylgalactosaminidase from the culture of medium of Diplococcus pneumoniae". J. Biochem. (Tokyo) 80 (1): 1–8. July 1976. doi:10.1093/oxfordjournals.jbchem.a131240. PMID 9374.
- "Purification and properties of an endo-alpha-N-acetyl-D-galactosaminidase from Diplococcus pneumoniae". J. Biol. Chem. 252 (23): 8609–14. 1977. PMID 21877.
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