Biology:Poly(ADP-ribose) glycohydrolase
From HandWiki
| Poly(ADP-ribose) glycohydrolase | |||||||||
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| Identifiers | |||||||||
| EC number | 3.2.1.143 | ||||||||
| CAS number | 9068-16-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- hydrolyses poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose
Specific to (1''-2') linkage of ribose-ribose bond of poly(ADP-ribose).
References
- ↑ "Splitting of the ribose-ribose linkage of poly(adenosine diphosphate-robose) by a calf thymus extract". The Journal of Biological Chemistry 246 (20): 6362–4. October 1971. PMID 4331388.
- ↑ "Isolation and characterization of the cDNA encoding bovine poly(ADP-ribose) glycohydrolase". The Journal of Biological Chemistry 272 (18): 11895–901. May 1997. doi:10.1074/jbc.272.18.11895. PMID 9115250.
External links
- Poly(ADP-ribose)+glycohydrolase at the US National Library of Medicine Medical Subject Headings (MeSH)
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